A 18year old with Shortness of breath, Right sided hearing loss

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An 18year old girl from Suryapet came with the complaints of shortness of breath since 2/8/22 morning which increased by the evening. She also has abdominal pain in right upper quadrant and vomitings.

History of presenting illness:

Patient was apparently asymptomatic 3months ago. Then she developed shortness of breath (grade 4) and pedal edema upto the level of below the knees(pitting type) and facial puffiness.
She also had fever and vomitings for which she was taken to a hospital and was said to have some infection for which she was given medication(unknown).
3 days back(on 2/8/2022 morning) she developed shortness of breath which increased by 3pm (grade 4) and went to a Government hospital and then came to our hospital.
She also had pain in the abdomen right upper quadrant which was dull aching type, non radiating associated with 2 episodes of vomiting which was non projectile, non bilious, associated with nausea and with food as content.
Patient also complaints of decreased hearing in right ear since 4 years associated with ringing sensation.
History of trauma to right ear 4 years ago.

Past history:

Not a k/c/o hypertension, diabetes, asthma, epilepsy, CAD, Thyroid disorders.

Personal history:

She has normal appetite, takes vegetarian diet, bowel and bladder movements are regular, sleep is adequate and no addictions.

Daily routine:

She wakes around 7am in the morning, does house chores like cleaning, have her tea at 8am and her breakfast at 9am. She resumes with her household work and eats her lunch at 2pm, watches TV and takes a nap. Later in the evening she plays with her brothers’ kids and eats her dinner at 9pm and sleeps at 11pm.

Family history:

No member of the family has similar complaints

General examination

She is conscious, coherent and cooperative 

She is ill built and poorly nourished 

She has pallor



No icterus, cyanosis, clubbing, lymphadenopathy and pedal edema 

Clinical images






Vitals

Temperature: Afebrile 

Pulse rate:90bpm

Blood pressure:120/80mmHg

Respiratory rate: 20cpm

Systemic examination:

Respiratory system examination:

Bilateral air entry+

Normal vesicular breath sounds heard 


Cardiovascular system examination:

S1 S2 heart sounds heard, no murmurs 


Per abdomen:

Scaphoid, no distension 

Soft, nontender 

No organomegaly


Central nervous system examination:

Higher mental functions intact 

No focal neurological defecits


Ear examination:

                                      Right                       Left

Preauricular area         normal                   normal

Pinna                           normal                   normal

Postauricular area       normal                   normal

EAC                            Clear                      Clear

Mastoid tenderness     Absent                  Absent 

Tympanic membrane     Intact                  Intact 

Tuning fork tests 

Rinne test              

      256Hz                     +                            +

      512Hz                     +                            +

      1024Hz                  +                            +

Weber test                   Lateralised to left

ABC                           reduced                  reduced 



Provisional diagnosis:

Chronic kidney disease 

Alport syndrome?

Bilateral sensorineural hearing loss 

Investigations:

On 3/8/22







On 4/8/22

After blood transfusion on 04/08/2022





On 6/08/2022

After hemodialysis







Treatment:

Fluid and salt restriction
Inj.ERYTHROPOIETIN 4000IU weekly twice
T.NODOSIS 500 mg PO/BD
T.SHELCAL 500mg PO/OD
T.OROFER- XT PO/OD
Cap.BIO D3 PO weekly once 
Inj.LASIX 20 mg IV/BD (If SBP greater than 110mmHg)
Inj.CEFTRIAXONE 500mg IV/BD
BP monitoring 4th hourly


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