A case of 36yr old male with jaundice

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.

A 36 yr old male presented to the OPD with C/O yellowish discolouration of  eyes and passage of dark yellow coloured urine since 1month.

HOPI

Patient was apparently asymptomatic one month ago then he went to village for some occasion and developed fever and cough and was passing dark coloured urine. He visited a hospital and was diagnosed to be ?liver failure ( Total bilirubin- 5gm/dl) . 3 days later after getting back from the village he went to a hospital in Miryalaguda and then total bilirubin was 10 gm/dl for which he was given medication and alcohol abstinence. The patient continued drinking after completion of medication.He also used herbal medication for 9days but as he developed itching all over the body, he stopped taking the herbal medication.


Past history 

The patient is not a known case of hypertension, diabetes, TB, epilepsy, asthma, CAD

He is a welding worker by occupation. He has normal appetite, mixed diet, regular bowel and bladder movements, adequate sleep. He is taking alcohol from last 20 years. He takes 180-360ml alcohol daily. He used to smoke 3cigerettes per day. He stopped smoking 4 years ago. 

General examination 

The patient is conscious, coherent and cooperative 

He is moderately built and nourished

Vitals

Temperature: 98.6degree F

PR: 90bpm

BP: 120/70 mmHg

RR: 18cpm

SpO2: 98%

Icterus+

No pallor, cyanosis, clubbing, lymphadenopathy, edema








On examination 

P/A   Obese, non tender, no scars, no sinuses, hernial orifices free

Mild hepatomegaly

Splenomegaly

CVS   S1 S2+

RS     Bilateral air entry+, normal vesicular breath sounds+

CNS   NFD


PROVISIONAL DIAGNOSIS 

Chronic liver disease secondary to alcohol?


INVESTIGATIONS

13/11/2021
CBP
HB- 10.2
TLC - 7800
PLT - 1.57
LYMPHOCYTES - 12

LFT
TB- 15.9
DB - 7.10
AST - 366
ALT - 71
ALP - 358
TP- 7.2
ALB- 3.0
A/G - 0.71

CUE
COLOR - BROWNISH
APPERANCE - CLEAR
ALBUMIN - TRACE 
SUGARS - NIL
BILE SALTS - NIL
BILE PIGMENTS - NIL
PUS CELLS - 2-4
EPITHELIAL CELLS - 1-3
RBC - NIL

BLOOD UREA - 12 
S. CREATININE - 0.5

14/11/2021
CBP
HB - 9.9
TLC - 8300
PLT - 1.52

16/11/2021
LFT
TB - 13.79
DB - 12.11
AST - 201
ALT - 46
ALP - 513
TP - 6.2
ALB - 2.6
A/G - 0.73

Chest Xray PA view 


USG ABDOMEN



ECG


Treatment 

Tab. UDILIV 300mg BD

Tab. MVT /PO/OD

Syp. LACTULOSE 15ml/PO/H/S

Inj. LORAZEPAM 2c.c /IV/SOS

IV Fluids (NS,RL,DNS) @50ml/hr

Tab. RIFAGUT 550mg BD

Inj. VITK 10mg/slow IV/ OD



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